https://www.thelancet.com/journals/lanpsy/article/PIIS2215-0366(25)00129-4/abstract
Interpretation
Semaglutide led to significantly greater weight loss than placebo in this small trial without affecting psychotic symptoms or clozapine concentrations. Semaglutide appears to be safe and well tolerated in this population. These encouraging findings highlight the need for larger confirmatory trials.