I’m just curious if you gained weight on Wellbutrin?
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I take wellbutrin and haven’t experienced any weight problems. Good med in my opinion.
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Thanks @Natron.
When I was on Wellbutrin I didn’t really gain weight. But I was also on Adderall which was suppressing my appetite
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No. I didn’t gain weight on Wellbutrin. It even gave me the energy to exercise more.
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I never took it.
In my life I took a total of 3 antidepressants. Paroxetine, sertraline and luvox. With the only antidepressant that I did not gain weight was with luvox.
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Thanks @Noise @TheFountainPen and @Nirvana for telling me your experience.
My pdoc prescribed it for concentration. It’s up to me if I want to take it though.
Having more energy would be nice @TheFountainPen. Ever since I had Covid, I feel tired during the day. However, I don’t need naps like I did during Covid and right after recovering.
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Wellbutrin boosts dopamine so it can have that activating effect. In the beginning my voices were a bit louder but it settled down.
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Definitely not it reduces your appetite and makes you lose weight. Only ad that really works like this since it’s the only as approved as ndri
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wellbutrin (bupropion) have low dopamine transporter occupancy according to some researches. i have doubts on its efficacy regarding dopamine reuptake inhibtion. what do you think?
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@MIDO my pdoc prescribed it for concentration. It was not prescribed for depression. However, it’s up to me to take it. I took one this morning. Hopefully it helps.
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@AmICrazyYet thank you. My niece lost weight on it too.
Yes weak occpancy, which is why it has indication for depression as it has low abuse potential because of this
I do not think they would use it in combination as weight loss agents unless they believe it had efficacy. More over simply combing 2 medication together which make smaller effect in combination threapy allows them to patient it.
They have done the same thing with Samidorphan Olanzapine. I would think if you are looking at that medication you could just take generic zyprexa and Naltrexone/bupropion to get a better effect but I’m no doctor.
Naltrexone/bupropion are both anti-addiction medications so it reasons that they will curbe addictive eating relate to dopamine. In reality it is more simple then that it is a stimulant and thus reduces appetite. They used to prescribe speed/amphetamines as diet pills. Obviously they can’t recommend it for this indication but stand to reason it should produce a small but maybe not robust effect.
If you look at Phentermine you will see it is basically the replacement for prescribing people speed as a weight loss medication. This is mainly to do with societal expectation around regulation of drugs and political domga raise the war on drugs itself. It has little to do with medication or chemical itself. I wouldn’t really recommend using something like Phentermine to lose weight. Nor would I recommend Bupropion for this but if in the example of antipsychotics you have high bmi disturbances and risk of type 2 diabetes, you have depression and negative symptoms then it can be a useful agent.
You’re not going to get high off Bupropion because of the low dat occupancy. In answer the question does it make you lose weight it is the question is harder to answer. But in answering the question the it make you gain weight the answer is surely not.
Things which are stimulants generally reduce appetite and things which are more sedating generally increase you appetite and make you gain weight. A junior pdoc told me that the more sedating antipsychotics have a higher propensity to make you gain weight. So if you want a antipsychotic with a low weight gain profile then something which not only has low weight profile but also low sedation is best. You can see this relationship holds true for worst offenders quetiapine/Olanzapine vs abilify/geodon/latuda.
The same relationship would probably hold true for Bupropion vs Ritalin
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