Depression FINALLY lifted after over 20 years

I hope to not look a gift horse in the mouth, but for the first time since I was 11, my depression has lifted. The SSRIs all failed me, going all the way back to when Paxil first came out in 1994. My lucky med this time is Sinequan (doxepin). It’s a tricyclic antidepressant and is VERY powerful and works a lot faster than the 4-6 weeks in take SSRIs going.


well, that’s great news alien99 !! I learned some tricks about not looking back in the past so much and have been much happier lately too because of that plus all the visits from sister and mom cheer me up too. Glad to hear you are out of depression. wow.

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Alien99, it’s great you can get rid of depression now. What was the result of you seeing doctor on this Monday? Did they put you back on antipsychotics again?

@green6, I saw my neurologist on Monday, and he is also board-certified in psychiatry. This guy is top-shelf. He put me on a small dose of Prolixin to take until SEPT 2, when I see him again. He added a med called Keppra, which is an anti-seizure med in its own right, but works best with another anti-seizure med (in my case, it’s Depakote). It’s knocked out the migraines, so if for no other reason, I’m staying on it for a long time! :smiley:

I am not familiar with Prolixin. Actually haven’t heard of it before. Is it an antipsychotics? Very happy that you feel much better now with the migraines. It’s fantastic!

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@green6, Prolixin is an ancient med (came out in the 50s), but is pretty low on side effects. Its generic name is fluphenazine. It also comes in shot form, but I take the pills. I hate injections!

I too am on prolixin…

so happy to hear you are feeling better. depression literally sucks the lifeblood out of us.

really glad for you and us that know the feeling of finally feeling some happiness again.


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Sometimes older meds are the right tool for the job. I’ve been on a couple of them in the past, Anafranil, Imipramine. Very powerful stuff.

This is some great news alien! I was on another tricyclic antidepressant, Imipramine - very strong
I am glad to hear that your migraines are under control, Keppra is another tried and true medication for seizures

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thats great alien :slight_smile:

its amazing what can happen when you are on the right meds :slight_smile:

good for you