I’ve used Creatine to help lift weights. It really did help. I’ve never used Creatine monohydrate for mental illness and cognitive function. Seems promising.
modestly augmented the antidepressant-like behavioral effects of dietary creatine in female rats
Decreased metabolic activity diminishes the brain’s ability to efficiently generate or process neural signals, which may account for the positive or negative symptoms of schizophrenia described above. Consistent with this evidence of impaired metabolic processes, abnormalities in the creatine-phosphocreatine pathways have also been observed within emotional and executive brain regions of schizophrenic patients. Additionally, some studies have found an association between creatine metabolism and cognitive function in schizophrenia, generating much interest in the role creatine plays in the pathogenesis of the disorder.
Nevertheless, it is becoming increasingly evident that endogenous creatine plays a critical role in a range of cognitive functions, including learning, memory, attention, speech and language, and possibly emotion.
Creatine supplementation is generally considered safe and well-tolerated by humans and animals