Clozapine AND Seroquel?

I’m very interested in asking my psychiatrist about starting clozapine during my Tuesday appointment. I am currently taking 400 mg of Seroquel XR which doesn’t work for my positive symptoms. I’m not sure if I can take both clozapine and Seroquel together: does anyone take this combination?

@binarybipolar

I don’t take that combination.

Generally speaking, taking two or more anti-psychotics at the same time (polypharmacy) is not a good idea for various reasons.

Check with your pdoc.

I currently am taking two antipsychotics–Rexulti and Seroquel XR; hopefully she can get me off of Rexulti and onto Clozapine. It’s unfortunate that I am not seeing progress with the Seroquel and Rexulti.

400mg is quite a low dosage. Perhaps try a meds increase?

I have a friend who takes them and venlafaxine and it keeps him well.

Do you know much about clozapine? Weekly blood tests etc?

I know clozapine is sort of a last-resort and requires consistent blood work. I take lithium so I’m used to the blood work.