Which antipsychotics improve working memory and executive functioning apart from risperidone ?
Pretty much all of them, right? I think I noticed the most on latuda and vraylar.
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well not all of them improve working memory, so far I’m aware that risperidone extremely improves working memory[1]
[1] http://schizophreniabulletin.oxfordjournals.org/content/25/2/233.full.pdf
I haven’t tried a single AP that improves those things, all they do for me is get rid of delusions and lessen hallucinations. My negative symptoms are always there.
I went to speech therapy and did cognitive training that improved my working memory. I had a TBI though, so my services were covered.
I noticed improvement in my executive functioning after starting sarcosine, which I’ve been taking for almost two years now.
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My EF is poor (NB organising and planning,doing multi step tasks). Years ago I did an online cognitive assessment mentioned by sz admin . I scored average or above in everything but EF. For that I was 1.5 to 2 SD below average. I’ve not found that any AP has made a great difference when it comes to EF for me.
@insidemind You were right. Just got a text from the pdoc, he suggested lurasidone for cognition. But the only downside i see is that it must be taken with food or else absorption is reduced by 50%. I dont know how can i consistently take it with food.
Is it sedating ? What if i eat food early like 7-8pm and take lurasidone immediately after dinner. I would prolly fall sleep immediately after dinner
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One man’s food is another man’s poison. Latuda was too weak for me. I got headaches, didn’t always eat with food, but I didnt feel medicated and my cognition improved.
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@insidemind What dose u took ? Did u take anything for EPS symptoms - trihexyphenidyl or benztropine
Like 180 mg of latuda and moderate, unknown dose of risperdal. It didnt help me. I took nothing for EPS. it felt like water or a placebo in the beginning. I felt good. This was in 2015 when I was at my worst with 10/10 paranoia. A former forum member, the mouse guy, said latuda is like water for someone truly schizophrenic.
@insidemind Well good thing in my case is that my positive symptoms(paranoia) are already controlled well by clozapine 225mg . But my cognition is kind of bad. So I’m only considering adding other antipsychotics to clozapine like risperidone or lurasidone which improve cognition.
Pdoc said low dose of lurasidone may help cognition
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Could it be possible that your cognition improved cuz of risperidone since you were taking both risperidone and lurasidone at the same time ?
I really don’t know. There was one time a few years ago, I was on some cocktail of meds that enabled me to recite pi to 100 digits for 2 weeks, memorize 7 license plates at a time, remember streets backwards and forwards during a 30 minute route, and do 500 hard math problems and puzzles.
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Well I will try lurasidone. I will prolly have to eat dinner just before bedtime so that I absorb lurasidone totally.
I wish I could take risperidone. I had huge anxiety attack on 0.5mg and started crying. Other forum members reported the same side effect on risperidone, one guy said he had huge panic attack on 1st risperidone dose. But it eventually goes away in few days and your body gets used to it. Well I can’t cry like this everyday at home, other family members would prolly get fedup with me and kick me out of the house
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Anybody would like to add any antipsychotic which helped their cognition ?
Possibly seroquel might be cognitive neutral. I think the ad fluoxetine may thinking a bit easier (purely from my own experience)
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Seroquel helps my cognition, Latuda did too. Asenapine should in theory be good for cognition, not sure though.
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Did lurasidone help?