A review on the relationship between gluten and schizophrenia: Is gluten the cause?

anon79999497 · April 11, 2017, 2:10pm

DISCUSSION: There were no consistent results in the clinical, immunological, microbiological, and epidemiological studies that investigated the relationship between schizophrenia and celiac disease. This presents a need for a larger scale study to confirm the presence of this suggested correlation between schizophrenia and celiac disease. The underlying mechanisms between the two diseases should be explored.

ncbi.nlm.nih.gov

A review on the relationship between gluten and schizophrenia: Is gluten the cause?

C Ergün, M Urhan and A Ayer, Nutritional neuroscience, Apr 2017 09

Schizophrenia is a chronic disease that possesses various clinical manifestations. It presents rather heterogeneous characteristics with respect to onset type, symptoms, and the course of the disease. Although the lifetime prevalence is as low as 1%, it can cause serious disability. Thus, it is very important to develop efficient treatment methods. In some studies, it is hypothesized that removing gluten from the diet leads to a significant improvement in disease symptoms. Epidemiological studies revealed that the prevalence of celiac disease among schizophrenic patients is almost two times higher than that of the general population.In this review, we evaluate the effects of gluten and celiac disease on the onset of schizophrenia. Efficacy of gluten-free diet applications, antibody response against gluten, and the interaction of the brain-gut axis and the presence of common genetic points are also investigated.Without any publication date restriction, Pubmed database searches were made for 'schizophrenia, gluten, gliadin, celiac disease, exorphin, brain-gut axis, psychiatric disorders.' The keywords and the articles about the schizophrenia-celiac disease relationship are included in our review.Several studies presented evidence to suggest that symptoms associated with schizophrenia were minimized when gluten was excluded from patients' diets. Immunological searches revealed that most schizophrenic patients with increased anti-gliadin antibodies did not possess celiac disease; yet, the presence of increased antibodies against gliadin can be the share point of the immunological abnormalities found in both of the diseases.There were no consistent results in the clinical, immunological, microbiological, and epidemiological studies that investigated the relationship between schizophrenia and celiac disease. This presents a need for a larger scale study to confirm the presence of this suggested correlation between schizophrenia and celiac disease. The underlying mechanisms between the two diseases should be explored.

anon70811669 · April 11, 2017, 4:13pm

I try to stay away from gluten and have for many years - no celiac, but I am intolerant. I’m sure over the long haul, I feel different as a result. I’ve told people that like my sister who took my nephew off of gluten because of autism. I definitely think there’s something important to this.

anon11056724 · April 11, 2017, 5:26pm

Maybe in another twenty years they’ll prove beyond the shadow of a doubt that there wasn’t any correlation between gluten and schizophrenia.
One can only hope

Hedgehog · April 11, 2017, 6:17pm

Why does it always seem like they’re grasping at straws?
Atleast they’re trying…?

y76 · April 11, 2017, 6:29pm

They always have found THE cause but we know it is MULTI-causal.

anon17132524 · April 11, 2017, 6:34pm

I have to give the “scientists” points for creativity.

The next scientific study should focus on whether eating too many Twinkies is the cause of schizophrenia.

Csummers · April 11, 2017, 7:23pm

Allergies play a big factor in my moods, and it’s not easy to figure out just what combination of stuff causes what .

anon70811669 · April 16, 2017, 5:03pm

Yeah, I miss gluten

Green · April 16, 2017, 5:15pm

I was gluten free for 8 weeks, but there was no change in schizophrenia symptoms. Unless you have to go longer I don’t know.

anon1571434 · April 16, 2017, 7:14pm

I don’t think I really ate much leading up to my first episode. I did smoke a lot of weed and drink a lot of coffee though. There might have even been lsd the weed was dipped in.

anon40653964 · April 16, 2017, 10:35pm

I don’t know if gluten relates to schizophrenia. What I do think though is that processed foods affect physical health and that probably CAN affect mental health. It’s like cutting cocaine, but with food, mostly meant to make profit and not meant to improve nutrition. I think I should eat more bananas.

twinklestars · April 17, 2017, 1:27am

I get confusion and depression as symptoms from allergies.

But I’m not allergic to or sensitive to wheat.

I did try going gluten free. Lost weight (because guess what, no pizza) but other than that, nothing.

TheNicestFreak · April 17, 2017, 4:31am

I actually have Celiac disease. Following the diet helped me lose weight (my innards weren’t destroying themselves anymore) but it had no effect on my hallucinations. Actually almost nothing has. Rexulti might be helping slightly.

shutterbug · April 17, 2017, 4:33am

Most of the people who avoid gluten are a damn sight crazier than I am. Less functional, too.

TheNicestFreak · April 17, 2017, 4:37am

I wish domino’s made a pizza that actually was guaranteed gluten free for Celiacs rather than people who are just doing it because they think it may help. I tried it anyway and probably got glutened.

Wrong Forum, maybe.

Bee3 · April 17, 2017, 6:29am

I tried a gluten-free Pizza once. It was disappointing. Celiac does run in my family though, which I guess should make me go hmm.

Green · April 17, 2017, 1:53pm

I feel sorry for celiacs.

thomas · April 17, 2017, 2:41pm

read stuff like this, tried a gluten free diet for 2 months, very strict. no changes so i went back to normal diet, and again no changes.