" Monroe: I have some mixed thoughts. We always think as clinicians, ‘Oh, a new drug is out there. I’m going to use this for my most difficult client, that nothing will work for them, and now this is a new thing, let me try it.’
I want to provide some caution around that we know that about 30% of clients with schizophrenia may be treatment resistant, and that may not be solely due to a dopaminergic problem. So, there is a dopaminergic dysfunction in most patients with schizophrenia, but in those treatment-resistant cases, it may not just be dopamine; it may also be other things like glutamate. And so, there is a reason why we should provide some caution for something like clozapine."
I took clozapine for a week I just kept passing out. Cobenfy from reviews seem harsh. I probably won’t be taking cobenfy as it’s expensive and anything like a med taken in my past. Good luck.
It has a better average score than most partial agonist antipsychotics, and better than antagonists. But more reviews are needed. I really don’t know what to think about this medication.
I need a relatively lower dose of a heavy hitter like risperidone (3mg) to remain stable mood wise.
A lightweight like Cobenfy probably wouldn’t cut it for me.
Yes its meant to be low side effects and efficacy… not meant to replace clozapine… dont know why so many people think it will replace clozapine, even the effect size indicates that its at most replacing olanzapine and risperidone