Whats the difference between Alzheimer psychosis and schizophrenia?

Medications
1

Why can’t Nuplazid be prescribed for schizophrenia if its considered an antipsychotic?

2

Its being researched for sz. Maybe sz is caused by different brain receptors.

3

One difference is that AP’s prescribed to people with dementia can lead to death.

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4

Okay, that’s not what I asked though… my question is if Nuplazid is an antipsychotic why can’t it be used for schizophrenia?

5

Its in phase 3 for sz negative symptoms:

6

That’s great still doesn’t answer my question.

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7

Well probably even scientists and Drs dont know.
My guess is that Alzheimer/Dementia psychosis is caused by brain damage, its neurological and doesnt involve dopamine. Different brain receptors are involved in sz vs other psychosis. I read that in Parkinson too little dopamine causes psychosis from dopamine neurons damage/death.

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8

Probably because it hasn’t been approved by FDA for treatment of Schizophrenia yet?
Maybe it will be.
Seems like it is mostly used for Parkinsons related hallucinations and delusions currently.

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9

It might be in 2023 when the study I posted ends.

10

What’s one more drug anyway? Does it have any benefits over our current slew of choices?

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11

Yea, it doesnt act on dopamine receptors directly so maybe less side effects but honestly all these non dopaminergic drugs still reduce dopamine, just in a indirect way by acting on different receptors that indirectly control dopamine.

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