Why can’t Nuplazid be prescribed for schizophrenia if its considered an antipsychotic?
Its being researched for sz. Maybe sz is caused by different brain receptors.
One difference is that AP’s prescribed to people with dementia can lead to death.
Okay, that’s not what I asked though… my question is if Nuplazid is an antipsychotic why can’t it be used for schizophrenia?
Its in phase 3 for sz negative symptoms:
That’s great still doesn’t answer my question.
Well probably even scientists and Drs dont know.
My guess is that Alzheimer/Dementia psychosis is caused by brain damage, its neurological and doesnt involve dopamine. Different brain receptors are involved in sz vs other psychosis. I read that in Parkinson too little dopamine causes psychosis from dopamine neurons damage/death.
Probably because it hasn’t been approved by FDA for treatment of Schizophrenia yet?
Maybe it will be.
Seems like it is mostly used for Parkinsons related hallucinations and delusions currently.
It might be in 2023 when the study I posted ends.
What’s one more drug anyway? Does it have any benefits over our current slew of choices?
Yea, it doesnt act on dopamine receptors directly so maybe less side effects but honestly all these non dopaminergic drugs still reduce dopamine, just in a indirect way by acting on different receptors that indirectly control dopamine.