Treating schizophrenia during menopause

anon79999497 · May 3, 2017, 9:51pm

ncbi.nlm.nih.gov

Treating schizophrenia during menopause.

A Brzezinski, NA Brzezinski-Sinai and MV Seeman, Menopause (New York, N.Y.), May 2017

The aim of this review is to examine three questions: What are the risks and benefits of treating women with schizophrenia with hormone therapy (HT) at menopause? Should the antipsychotic regimen be changed at menopause? Do early- and late-onset women with schizophrenia respond differently to HT at menopause?MEDLINE databases for the years 1990 to 2016 were searched using the following interactive terms: schizophrenia, gender, menopause, estrogen, and hormones. The selected articles (62 out of 800 abstracts) were chosen on the basis of their applicability to the objectives of this targeted narrative review.HT during the perimenopause in women with schizophrenia ameliorates psychotic and cognitive symptoms, and may also help affective symptoms. Vasomotor, genitourinary, and sleep symptoms are also reduced. Depending on the woman's age and personal risk factors and antipsychotic side effects, the risk of breast cancer and cardiovascular disease may be increased. Antipsychotic types and doses may need to be adjusted at menopause, as may be the mode of administration.Both HT and changes in antipsychotic management should be considered for women with schizophrenia at menopause. The question about differences in response between early- and late-onset women cannot yet be answered.

http://sci-hub.cc/10.1097/GME.0000000000000772

metime · May 5, 2017, 1:34am

Thanks for looking out for us ladies @firemonkey!

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Treating schizophrenia during menopause

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