The purpose of this research study is to:
Test the effect of the study drug (pimavanserin) compared to placebo (an inactive pill) when added to ongoing antipsychotic medication on symptoms of schizophrenia.
Evaluate the safety of pimavanserin and how well you tolerate it.
Currently, pimavanserin is only approved for use as Nuplazid in patients with Parkinson’s disease psychosis. Psychosis is defined as seeing or hearing things that are not really there (hallucinations) and false or mistaken beliefs (delusions). Nuplazid is not approved for the treatment of patients with dementia-related psychosis unrelated to the hallucinations and delusions associated with Parkinson’s disease psychosis. It is still being studied as an adjunctive (added or additional) investigational drug for schizophrenia patients who continue to experience symptoms even while taking ongoing medication. An investigational drug is one that is not approved by the US Food and Drug Administration (FDA), or its use in patients with other illnesses is not approved by the US FDA.
As part of this study, safety and tolerability (how well a person can handle a drug) of adjunctive pimavanserin in subjects with schizophrenia will be evaluated. Because this is a research study, the study drug will be given to you only during this current study.
https://acadiastudynow.com/patient/qualify
https://acadiastudynow.com/patient/research