I had no friends as a teenager. I was probably the most unpopular boy to ever go to my British public school .
Same, except for the part about being a boy, and British.
We find one population of neurons, parvalbumin expressing inhibitory neurons, increases in activity prior to an active, but not a passive social interaction. Brief activity of these neurons is sufficient to promote increased active social behavior. Juvenile social isolation during adolescence disrupts the activity of these neurons, leading to a decoupling of their activity and subsequent active social behavior initiation. Increasing activity of these neurons in adult animals that were socially isolated during adolescence restores normal social behavior.
That’s the same type of neuron Drs Lodge and Donnegan are working with in their stem cell treatment model.
https://www.nature.com/articles/s41467-020-14740-z
We validated that 40 Hz blue light stimulation can reliably induce spiking in dmPFC PVIs
Interesting.