Magdalena Biosciences aims to submit an Investigational New Drug application to the FDA in 2025

News
1

“The company aims to submit an Investigational New Drug (IND) application to the FDA in 2025, with 1-2 additional applications planned for late 2025/early 2026. MB2500 is derived from a well-characterized plant with historical use and demonstrated neuroprotective and cognitive enhancing properties.”

8 Likes
2

The well characterized plant it is based on is called the

"Banisteriopsis caapi, also known as Ayahuasca, Caapi, or Yagé, is a perennial vine native to the Amazon rainforest. Here are some key characteristics:

  • Growth: It can grow up to 30 meters (98 feet) in length, climbing on other plants for support.
  • Stems: The woody stems are robust and can reach impressive lengths.
  • Leaves: The leaves are ovate, smooth-edged, glossy, and arranged oppositely along the stem.
  • Flowers: The flowers are small, typically white or pale pink, and bloom infrequently.
  • Bark: The bark is chocolate-brown and smooth.
  • Alkaloids: Contains beta-carboline alkaloids such as harmine, harmaline, and tetrahydroharmine, which act as monoamine oxidase inhibitors (MAOIs).
  • Traditional Uses: It is used in traditional spiritual and healing practices by indigenous tribes in the Amazon, often as part of the Ayahuasca brew.

It’s fascinating how this plant has been integrated into cultural practices for centuries! Have you heard about its use in Ayahuasca ceremonies?“” (Copilot)

Fascinating that it is used in Ayahuasca ceremonies whcih is of course a hallcinogenic one…

2 Likes
3

Can you imagine if the standard treatment for schizophrenia was based on a plant? There would be almost no side effects. No chemicals. It would be heaven. I hope we’re not far from that.

3 Likes
4

I was under the impression that in ayahuasca ceremonies people went on a vomiting stage purging up everything?

2 Likes
5

I honestly have no idea. I hope we get some news about this plant.

1 Like
6

You should read my fictional story about this plant which i referenced many years ago coincidentally.

It is free to read:

Av by Matthew Chard at Inkitt

Es en inglés pero te espero que puedes comprendelo

1 Like
7

what is the active ingredient in this plant that treat schizophrenia?and what its mechanism of action?

2 Likes