LB Pharma's twist on old Sanofi drug passes schizophrenia test, teeing up phase 3 push

https://www.fiercebiotech.com/biotech/lb-pharmas-twist-old-sanofi-drug-passes-schizophrenia-test-teeing-phase-3-push

The trial randomized 359 people with acutely exacerbated schizophrenia to receive one of three daily oral doses of LB-102 or placebo. LB-102 is a modified version of amisulpride, a dopamine inhibitor that was developed in the 1980s and marketed by Sanofi as a schizophrenia drug—Solian—outside the U.S.

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Amisulpride is a great med. I was on it for couple of months and it improved both my positive and negative symptoms I had to quit taking it becouse my prolactin levels were to high.

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i prefer discovering new drug rather than modifying an old one.

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LB-102 was safe and well-tolerated, with low extrapyramidal symptoms, adverse events linked to increased prolactin, and QT interval prolongation. Only 1 participant on LB-102 reported sedation.

What IS your country ? Because amisulpride IS not on the american market.
In France my country amisulpride IS named solian.

I am from Croatia.

Hello @petar_pan, i have a question ? I want an antipsychotics with not or few weight gain effect. Have you weight gain with amisulpride ?
My antipsychotics abilify IS good but i gained 10 kilograms with it.
See you soon and thanks for your answer.

   Sébastien from france

Hi.

Here is antipsyhotic weight gain chart.

Best regards.

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Thank @petar_pan.