Great find @everhopeful! The article distinguishes between treatment-resistant SCZ and other SCZ’s. A difference of " abnormal glutamate function."
It makes me think of all those small glutamate-based studies which showed promise. A lot of the treatments were later thought to be failures when tested in larger populations. Maybe a lot of glutamate-based treatments worked on treatment-resistant SCZ but failed in larger (more inclusive) SCZ populations. If so it would be time to revisit all those treatments.
Hopefully, any glutamate-based treatments which improve cognitive flexibility can help other mental illnesses too. Illnesses where the mind gets fixated, like OCD and perhaps even PTSD.
Thank you, it’s very interesting! Is there a link to the scientific publication in a journal? I can’t seem to find one.
It says
Cognitive control network connectivity differentially disrupted in treatment resistant schizophrenia was published 30th March in Neuroimage: Clinical
Maybe you can use google to track it down?
Thank you! I’m multitasking and thus failed to notice this sentence. I’ll google it down.