‘‘Gastrointestinal adverse effects, such as nausea (NNH = 7) and vomiting (NNH = 9), were evident. Discontinuation due to these AEs was relatively low (NNH = 49). KarXT did not significantly affect weight gain or cause somnolence, unlike many existing antipsychotic medications’’
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Let us hope KarXT will be a revolution in psychiatry like chlorpromazine and clozapine were.
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I wonder what used to happen before those treatments?
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I don’t know. Those were some horible times for schizophrenia patients.
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They were thrown into insane asylums.
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Dam, I hope KarXT spurs a revolution, and we can say that 10 years later we used to take terrible drugs before KARxt was introduced.
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chlorpromazine was originally marketed a chemical lobotomy and does not have that affect on most people but can still do brain damage.
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I don’t know why pdocs don’t start off with clozapine if it’s treatment resistant! Maybe get new pdocs
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