Pity its not something men can use, but atleast its something.
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They are looking at selective estrogen receptor modulators in men though.
MR Khodaie-Ardakani, M Khosravi, R Zarinfard, S Nejati, A Mohsenian, M Tabrizi and S Akhondzadeh,
Acta medica Iranica , 2015
Selective estrogen receptor modulators (SERMs) such as raloxifene have already shown beneficial effects on negative, positive and general psychopathology symptoms in postmenopausal women with schizophrenia. The purpose of the present investigation was to assess the efficacy of raloxifene as an adjuvant agent in the treatment of men with chronic schizophrenia in an 8-week double-blind and placebo-controlled trial. In a randomized, double-blind and placebo-controlled study, forty-six male patients diagnosed with schizophrenia (DSM-IV-TR), were randomized to either raloxifene (120 mg/day) or placebo in addition to risperidone (6 mg/day) for eight weeks. The assessment was performed using the positive and negative symptom scale (PANSS) at baseline, and at weeks 2, 4, 6 and 8. Extrapyramidal symptom rating scale (ESRS) at baseline, weeks 1, 2, 4, 6, 8 and Hamilton depression rating scale (HDRS) at baseline and week 8 were also used to assess extrapyramidal symptoms and depression simultaneously. Forty-two patients completed the trial. The raloxifene group showed significantly greater improvement on the negative subscale (P<0.001), the general psychopathology subscale (P=0.002) and total PANSS score (P<0.001) in comparison to the placebo group at the endpoint. There was no significant difference in the reduction of positive symptoms score between the two group (P=0.525). Extrapyramidal symptom rating scale and Hamilton depression rating scale and frequency of other adverse effects were comparable between two groups.This study indicates raloxifene as a potential adjunctive treatment strategy for chronic schizophrenia in men.
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DNA
August 2, 2019, 10:30pm
4
I read that Schisandra Berry Extract increases estrogen.
https://www.ncbi.nlm.nih.gov/m/pubmed/15256741/
I have a few grams of this stuff from ND. Haven’t noticed much when I was trying it. Maybe it doesnt have that great effect on men.
Itd be interesting to know its effects on SZ women.
Green
August 3, 2019, 7:56am
5
Raspberry leaves are a natural serm (selective estrogen…something). I remember reading about it years ago.
I’ve still got a full bottle of raspberry leaf extract to try.
Serms modulate estrogen.
I had a complete hysterectomy and was put on low-dose estrogen. I don’t know about its effects on psychosis symptoms but it’s done wonders for the mood swings I would experience during my natural “cycle”. I used to literally get worsening psychosis about 3 days before my period. I’m glad they took it all out.
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