Intra-Cellular Therapies Announces U.S. FDA Approval of CAPLYTA® (lumateperone) for the Treatment of Bipolar Depression in Adults

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Agonists like Abilify and Vraylar made me unstable.
Vraylar landed me in the hospital twice.

Caplyta will be no different.

These meds make me manic and very anxious.

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" It is a potent serotonergic (5-HT2A) antagonist, partial agonist at presynaptic dopamine receptors and antagonist at postsynaptic dopamine receptors."

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The first time I was on Abilify it made me manic and worsened my symptoms. My pdoc eventually talked me into trying it again and now it’s working wonders. Very odd how meds do strange things

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For me Caplyta took awhile to start doing its job. Around 2 months. I’m glad I stuck to it mainly because it does not increase my appetite and hunger. I have read it has done so for others. I usually take it around 6 or 8 P.M. daily. If I take it later I cannot sleep for about 4 hours. After 4 hours it does put me to sleep. I’m not sure why it keeps me awake for 4 hours and then bam, I suddenly feel extremely drowsy and my eyes start drying out if I keep them open.

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That reminds me @Kader78 I apologize for not answering your question about my experiences with Caplyta so far. I had been meaning to do so. If you have any questions feel free to ask me here or if you have more personal concerns about it PM me.