H. Lundbeck A/S, a global pharmaceutical company specialized in psychiatric and neurological disorders, starts the clinical development of a potential new treatment of schizophrenia and Alzheimer’s disease. A phase I-study in healthy volunteers with the compound, invented by Lundbeck, has just begun, adding it to Lundbeck’s clinical pipeline.
A so-called PDE1-inhibitor, the compound Lu AF76432 addresses impaired communication between cells in certain parts of the brain that causes cognitive/functional deficits, e.g. the loss of concentration, loss of memory, the ability to learn and planning of daily tasks. Such cognitive symptoms are prominent in diseases like schizophrenia and Alzheimer’s disease, and Lu AF76432 has the potential to help ease these symptoms in patients suffering from these diseases.