Evaluation of hyperhomocysteinemia prevalence and its influence on the selected cognitive functions in patients with schizophrenia

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It could be more helpful to use folinic acid instead of folic, if the hypothesis proposed by Ramaekers et al. has any truth to it (they suppose that treatment resistance in some cases of depression and SZ is associated with “cerebral folate deficiency”)

To those who are confused about hyperhomocysteinemia, it is a condition with high levels of homocysteine. It’s often caused by folic acid and a gene mutation on the MTHFR gene.

In fact, I’ve found that OMIM has an “schizophrenia, susceptibility to” entry in regards the gene that causes this condition.
https://www.omim.org/entry/181500

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From Geneticoncept

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So do you have mutations in all these four genes? (Or variants?)

I think only 3 of the 4 are problem genes for me.

How do they work this out?

I’m not sure. There are several sites similar to geneticoncept. Being curious I joined a few. The thinking on such sites is that they’re not very good from a scientific perspective.

I was found to have low folic acid with my 1st blood test results here. I had never been told before that it was low. I take 1 400ug folic acid a day.

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Apologies for a late response to this.

It’s really figured out by gene sequences I believe. The proteins are supposed to pair up together in our DNA, but if a mutation occurs, it doesn’t lead the gene to do what it’s supposed to do.

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