We commonly think that progress in the cure of schizophrenia only depends on new antipsychotics but we could do drastically better with existing and older molecules but with an earlier intervention BEFORE PSYCHOTIC TRANSITION. It’s all about care organization&coordination : prevention is better than cure. This decisive stake consists in early detection of high risks cases during prodromal phase. The earlier is the intervention, the better is the prognosis. Definition and application of efficient preventive procedures is probably the most important line of work for mental health care community for the time being. This is of a tremendous importance.