New research suggests the two conditions may be de different outcomes of one genetic syndrome
Some researchers have suggested that the relatively high autism prevalence in this population is the result of misdiagnoses of early signs of schizophrenia.
The new findings, published 21 January in Schizophrenia Research, support an alternate theory: Autism and schizophrenia are independent outcomes of the same genetic syndrome.
If there is a relationship between the two conditions, “that can only be a very small, probably negligible effect,” says lead investigator Jacob Vorstman, assistant professor of child psychiatry and genetics at the University Medical Center Utrecht in the Netherlands.
The new findings could help guide clinical care, says Opal Ousley,
Interesting. I think a few here are on the spectrum and have sz/sz-a. At my last appt with the nurse practitioner I mentioned Aspergers and she offered up schizotypal as an alternative.
I can see a degree of both ASD and schizotpyal being related to me.
I knew this would be about deletion syndrome… I don’t remember the number but I suspected deletion syndrome on one chromosome or other because I have a cleft lip and palate and schizoaffective–both of which could be caused by it.
This is no surprise, either. My nephew has autism. While he was growing up, my sister would call me aggravated to no end that her son was “just like” me. He was. I’m sill delighted with her good fortune.
I don’t think I understand the article’s point. ASD and Schizophrenia are related? (I understand that they are) But being diagnosed with Autism as a child has no connection to being diagnosed with Schizophrenia later? That seems contradictory, so I must not understand what it’s saying.
My nephew was diagnosed with ASD. I told my brother about my sz diagnosis with the intent that he be prepared for it being a possibility for his son and/or daughter.
Here’s my take: Basically this article means to tell us that the link between ASD and Schizophrenia is now chromosomal, according to science.
It doesn’t mean much to me except that I was reading about deletion syndrome not terribly long ago.
Read on if you want less information:
I think the main point of this is that there is a deletion syndrome that is common to both. It’s different than it just being genetic, though I don’t know how–I think deletion syndromes are genetic… The deletion syndrome is a piece of a specific chromosome being deleted–I don’t know if that happens during fetal development or before…
I wish they didn’t use the word delete. It makes me feel like someone typed my chromosomes up and then did some editing.
Everything I type is long and a little off the mark right now. Sorry.
So, I understood the article?
I appreciate your synopsis. I don’t mind the word deletion, as long as it’s true and a step towards better understanding. But it’s almost like they don’t want to understand, or don’t want people who might freak out to understand?
I work with kids with ASD and they’re precious, every one, but even I’m over the royal status Autism has attained. God forbid it be associated with anything so horrible as sz.
My nephew was dangerous when he was a kid. I love him but that’s the truth. I was never a danger to others, even on drugs. But yeah, I’m a monster and he’s the Horse Whisperer. I totally agree with you about the status. It’s unwarranted.
