Only a case study.
The case study, published online April 24 in Biological Psychiatry , details how this procedure targets the substantia nigra pars reticulata—a part of the brain that’s a key hub of circuits involved in control of learning, executive functions and behaviors, and emotions. When this part of the brain is modulated using deep brain stimulation, it showed the potential to alleviate treatment resistant schizophrenia symptoms.
“Deep brain stimulation could be a game changer for schizophrenia patients who don’t respond to medication,” says lead author Nicola Cascella, M.D., assistant professor of psychiatry and behavioral sciences at the Johns Hopkins University School of Medicine, and faculty member at the Johns Hopkins Schizophrenia Center. “This is not a cure for schizophrenia. It’s an innovative way to treat the symptoms, and so far for our patient, the treatment is working.”