Wow!
Let’s see some studies in monkeys please.
“If you inject CRISPR DNA using a virus, you can’t control how much Cas9 protein and guide RNA are expressed, so injecting it via a virus has a potential problem,” Lee said. “I think the CRISPR-Gold method is very cool because we can control the amount we wish to inject and that probably minimizes the side effects of using CRISPR, for example off-target effects.”
“The technique opens the door to treating conditions ranging from opioid addiction and neuropathic pain to schizophrenia and epileptic seizures, Murthy said.”
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“CRISPR-Gold can be used to treat a variety of genetic diseases, such as Huntington’s disease,” Lee said. “But it’s not limited to monogenic diseases; it can also be used against polygenic diseases, once we figure out the entire network of genes involved.”
“Hye Young Lee, Kunwoo Lee and Murthy are now working to develop CRISPR-Gold particles that can be injected directly into the central nervous system via the spinal cord, avoiding the need to open the skull and inject directly into the brain. Hye Young Lee is optimistic that this could be as effective as intracranial injection”
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