Cognitive Deficit in Schizophrenia: From Etiology to Novel Treatments

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Some days I play guitar and I feel transparent because I don’t enjoy it. I am able to read though some days I’m as though in a dark room. I definitely feel impaired. My attention is laser focused but very tiny. I like to play some music I don’t enjoy listening to, in fact I have not enjoyed listening to music for a while.

It has also been observed that, in schizophrenic patients, there is lower M1 receptor binding in the hippocampus, which results in impaired learning [68].

Yesh, I have difficulties with learning (especially employment and whatnot). I need more M1 receptor binding in the hippocampus. Without question. This might take a long time. The meds I take don’t affect M1 receptors.

I don’t think it is as simple as I’m not learning right

That said pragmatically maybe KarXT will actually be able to help