I wish my hand didnt get so cold on the mouse!!!
They make “ergonomic mouses” that are easy on your hands and cause less cramping. I don’t know if the cold extremities may be caused by holding on too tight, or by circulation problems.
https://www.google.com/search?q=ergonomic+mouse&oq=ergonomic+mouse&aqs=chrome..69i57j0l5.9245j0j8&sourceid=chrome&ie=UTF-8