The study tested 2,500 mg citicoline (CDP choline) for 8 weeks in a placebo controlled study. Side effects were not significantly different between CDP group and placebo.
The supplement was used alongside risperidone.
https://www.ncbi.nlm.nih.gov/m/pubmed/29901250/
“CONCLUSIONS: Citicoline add-on therapy to risperidone can effectively improve the primary negative symptoms of patients with schizophrenia.”
Whoops, sorry I didn’t see that this was already posted.
How did they receive it?
A pill?
Liquid form?
In one portion or many?
At what time of the day?
I want to clarify that it’s possible to try it as a monotherapy, as well.
It’s a pill (rather, pills) and it doesn’t say if it was once daily or multiple times.
It was given alongside risperidone, although I don’t know any reason why you couldn’t take it without - but it’s not an antipsychotic and doesn’t have an effect on positive symptoms.
This study was not listed on clinicaltrials.gov which sometimes gives details like whether doses are divided.
There was another study though, using citicoline in schizophrenia, and they used 2,000 mg and divided it into 2 doses daily. They started with 500mg and worked up to 2,000mg over a week.
has anyone tried choline?
I took it for a few months. No luck for me
hmmm… might try it.