The number of lobotomies performed escalated from 150 in 1945 to more than 5000 in 1949; by 1951, more than 18 000 individuals had been lobotomized in the US. Shortly thereafter, the first effective medications were introduced. The first of these, chlorpromazine (Thorazine), was initially marketed in 1954 as a ‘chemical lobotomy,’ which produced apparently similar behavioral effects to lobotomy without the risks of surgery.
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The early medications at high doses could be considered that. Now there is a huge market for drugs like these that have no side effects. Newer medications have also failed there but not as bad. Older ones are still used but at much lower doses. APs change the brain significantly but I wouldn’t consider it a lobotomy.
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Oof I just looked up the effects of lobotomies
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Thank you for moving this post to “medications”
I have moved this post to the Medications category where it is a better fit. The Lounge is intended for general banter not related to the specific aspects of SZ/SZa, or the treatment of.
v.
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Lobotomies caused death and devastating effects. Many patients were left with permanent physical, mental, and emotional impairments. In the mid 1900s, lobotomies were largely replaced by psychiatric medicine.
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I don’t know but I think they are somewhat. F.x. Ziprasidone kept me awake for long times and the result of the Insomnia is that I find it hard to remember yesterday and reconicing faces.
But I simple get so lunar with less meds so that I by far prefere treatment (Lobotomy).
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In general, both first-generation and second-generation antipsychotics are very bad. They have too many side effects. That is why there is a high medication abandonment rate. Fortunately, third-generation antipsychotics are now coming, which will mostly target muscarinic receptors. For example KarXT, Emraclidine.
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I am on an older med, generic prolixin, fluphenazine…no side effects and highly efficient.
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That’s the way I view the typical AP’s. They are the death of all the creativity in your mind. If they ever want to put me on one of those again they are going to have to catch me first.
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What about 2nd generation?
I’m not familiar with that term. Do you mean 2nd generation typicals? or Atypicals?
Atypical like risperidone paliperidone abilify
Yes i have tried a long list of medications and the side effects have been pretty bad the best one i have tried is olanzapine but its still pretty bad 
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Lobotomy was permanent right? The effects of APs aren’t permament, but if you have to stay on APs for life, then maybe you could call it chemical lobotomy. ?
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Theyr like partial lobotomies lol 
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I don’t know about risperidone or paliperidone, but Abilify made me a little too antsy. They eventually had to take me off it. I’m doing pretty well on Geodon and Seroquel, so I want to rely on those drugs.
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İ heard it can cause permanent changes in the brain but i dont know how it causes the change and how much of it it causes
You know it’s a lot like a chemical lobotomy giving meth to children with ADHD. My experience was that it muted the crap out of my mind
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I’ve heard that too. And I also don’t know how serious it is. But I’m going to guess that even if you’ve been on APs for 30 years and you go off, your emotions will come back more to normal.
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