People with schizophrenia often engage in substance abuse as a way to self-medicate or alleviate feelings of anxiety and depression
Although substance abuse cannot cause schizophrenia, it can act as an environmental trigger. Someone with existing genetic risk factors for the disorder may develop an active case of schizophrenia after extended substance abuse. Using drugs, such as marijuana, cocaine and amphetamines, can also exacerbate schizophrenic symptoms and worsen their severity.