Treatment-resistant schizophrenia characterised by dopamine supersensitivity psychosis and efficacy of asenapine


Totally makes sense. If I look at it like abstaining from an intoxicant, tolerance drops significantly leading to a “stronger high”, in this case the “high” would be psychosis.

Even milder spikes could trigger someone with a brain thing, I would believe.

Good one E.H.

1 Like

My interpretation, group correct me if I’m wrong, is that treatment-resistant schizophrenia can be the result of long-term over medication?

1 Like