Transforming Clinical Recording of Deep Brain Activity with a New Take on

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  • The page reports a study published in the journal Nature Communications on a new approach to record deep brain activity with ultra-thin, flexible and customizable probes¹.
  • The probes are made of clinical-grade materials and equipped with sensors that can record extremely localized brain signals from large populations of individual neurons¹.
  • The probes are much smaller than today’s clinical sensors, allowing for high-resolution sensing in specific areas at unprecedented depths within the brain¹.
  • The probes can record with up to 128 channels, while the state of the art in today’s clinical probes is only 8 to 16 channels¹.
  • The probes are monolithic, meaning that their individual components are layered on top of one another to create a single, cohesive unit, and do not require manual assembly of additional wires to conduct recordings¹.
  • The new recording system is both extremely customizable and scalable to manufacture, thanks to thin-film technology derived from the semiconductor and digital-display screen industries¹.
  • The technology is a first step towards wireless monitoring of patients with treatment-resistant epilepsy for extended periods of time–up to 30 days–as they go about their daily lives¹.
  • The potential applications are much broader, including helping people with Parkinson’s disease, movement disorders, obsessive-compulsive disorder, obesity, treatment-resistant depression, high-impact chronic pain and other disorders¹.
  • The research team is led by the Integrated Electronics and Biointerfaces Laboratory (IEBL) at the University of California San Diego¹.
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