The impact of gender on treatment effectiveness of body psychotherapy for negative symptoms of schizophrenia: A secondary analysis of the NESS trial data

anon79999497 · November 22, 2016, 2:53pm

These findings suggest that body psychotherapy may be an effective treatment for negative symptoms in women.

ncbi.nlm.nih.gov

The impact of gender on treatment effectiveness of body psychotherapy for negative symptoms of schizophrenia: A secondary analysis of the NESS trial data.

M Savill, S Orfanos, R Bentall, U Reininghaus, T Wykes and S Priebe, Psychiatry research, Jan 2017

Despite promising findings from small-scale studies suggesting that body psychotherapy may be an effective treatment for negative symptoms, these results were not replicated in a recent multisite trial. In this trial a far smaller proportion of women were recruited relative to earlier studies, which may be an issue given the gender mix of the sample evaluated has been found to affect trial outcomes in schizophrenia. Using data from our multisite trial, the interaction between gender and treatment allocation as a predictor of outcomes was examined in 275 participants (72 women and 203 men) randomised to either a body psychotherapy or Pilates group. Negative symptoms were found to significantly reduce in women randomised to the body psychotherapy condition in comparison to Pilates, while no such effect was detected in men. Consistent with the smaller trials, this improvement was found to relate predominantly to expressive deficits. These findings suggest that body psychotherapy may be an effective treatment for negative symptoms in women. These findings emphasise the importance of sample characteristics in determining trial outcome in psychological treatment studies.

Topic		Replies	Views
Effectiveness of group body psychotherapy for negative symptoms of schizophrenia: multicentre randomised controlled trial News	1	926	May 7, 2016
Interactional synchrony and negative symptoms: An outcome study of body-oriented psychotherapy for schizophrenia News	1	701	October 1, 2016
Sex Differences in Clinical and Functional Outcomes among Patients Treated in an Early Intervention Service for Psychotic Disorders: An Observational Study News	0	215	June 14, 2019
Negative symptoms and recollections of parental rejection: The moderating roles of psychological maladjustment and gender News	0	249	April 8, 2019
The effect of mind-body and aerobic exercise on negative symptoms in schizophrenia: A meta-analysis News	0	205	March 31, 2020

The impact of gender on treatment effectiveness of body psychotherapy for negative symptoms of schizophrenia: A secondary analysis of the NESS trial data

Related topics