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“Although it remains unclear whether this potentially novel receptor-binding profile, particularly its serotonergic and glutamatergic activity, is clinically relevant, it raises the possibility that in addition to being a general treatment for schizophrenia, lumateperone may be helpful for a subset of treatment-resistant patients with schizophrenia,” Kantrowitz wrote.
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Here’s what I noticed: “Lumateperone was also associated with reduced extrapyramidal symptoms…”.
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