The primary endpoint is a decrease in Positive and Negative Symptoms Assessment total score compared to placebo from baseline to Day 28
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Looks like it’s an inprovment of abilify/aripiprazole structurally according to the wikipedia page.
I hope it’s good.
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I asked Bing AI if weight gain is a factor with brilaroxazine:
According to a press release from Reviva Pharmaceuticals, Inc., the company that developed brilaroxazine (RP5063), early clinical findings with brilaroxazine in schizophrenia and schizoaffective disorders indicate that this compound appears to be effective, well-tolerated, and possess a straightforward once-daily dosing pharmacokinetic profile1. In Phase 2 clinical trial results for acute schizophrenia, no metabolic side effects such as weight gain, elevated blood sugar, or increase in lipids were observed compared to placebo2. However, it is important to note that individual experiences may vary and it is always a good idea to discuss any concerns with a healthcare professional.
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