Pneumonia risk: approximately one-third is due to clozapine and two-thirds is due to treatment-ressistant schizophrenia

everhopeful · May 17, 2020, 9:07pm

ncbi.nlm.nih.gov

Pneumonia risk: approximately one-third is due to clozapine and two-thirds is due to treatment-ressistant schizophrenia.

AG Villasante-Tezanos, C Rohde, J Nielsen and J de Leon, Acta psychiatrica Scandinavica, May 2020 16

A recent umbrella review suggested that pneumonia is the most robust of the life-threatening medical events associated with antipsychotic use.1 More importantly, the literature suggests that clozapine appears to be more strongly associated with pneumonia than are other antipsychotics.2 However, clozapine is mainly prescribed in patients with treatment-resistant schizophrenia (TRS); therefore, the risk of pneumonia in clozapine patients is likely to be the result of the combined effects of TRS and clozapine.3 No published study has explored the relative contributions of these two factors.

y76 · May 19, 2020, 2:16pm

Chlorpromazine (thorazine) will be tested in France to fight covid19 pneumonia.

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Pneumonia risk: approximately one-third is due to clozapine and two-thirds is due to treatment-ressistant schizophrenia

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