Hi.
The prescription is 7.5mg of Olanzapine twice a day.
I have added L-theanine 100mg twice a day, and just increased it to 200mg as it is not affecting anxiety at 100mg dosage.
I have also ordered sarcosine, pregnenolone, lysine, NAC and these are en route.
How should I work these together ? Also, do these affect the potency of Olanzapine ?
Cheers.
Keep us updated…!!!
How much of the pregnenolone are you taking? Be careful with that one, although I found it effective for 3 months and then it stopped working (for cognitive/positive symptoms.) It’s a neurosteroid precursor I believe, and so it effects blood levels of testosterone. Hopefully shouldn’t effect libido too much, but you never know.
As for clozapine interactions, I have no idea. Try drugs.com
How do I edit the title ?
Its 7.5mg of olanzapine not clozapine. Sorry!
From the drugs website
Commonly reported side effects of olanzapine include: asthenia, dizziness, drowsiness, extrapyramidal reaction, hyperkinesia, akinesia, cogwheel rigidity, drug-induced parkinson’s disease, dyspepsia, mask-like face, and xerostomia. Other side effects include: abnormal gait, back pain, constipation, fever, orthostatic hypotension, weight gain, myoclonus, and personality disorder.
All I can say is WOW… Basically, its worth trying to replace this with supplements.
do not take sarcosine with clozapine!
that ap is like the only one that didnt work with sarcosine
and maybe there were some problems with that combo i cant remember
just search clozapine and sarcosine and youll find all info
Hypomania after augmenting venlafaxine and olanzapine with sarcosine in a patient with schizophrenia: a case study.
Strzelecki D1, Szyburska J1, Kotlicka-Antczak M1, Kałużyńska O1
Yup, Sarcosine does not work either with Olanzapine or Clozapine
Edited title and opening post to correct medication names.
Clozapine increases levels of pregnenolone, possibly this could be part of why it works. Anyway I don’t know if it would harm you but it’s probably not necessary to take both.
Good point twinkle, however AP is using olanzapine not clozaril. Too lazy to deal with a pubmed search on that one, but if someone asks me nicely…
Oh sorry maybe I got threads mixed up.
Or something. I can’t brain today.
It’s definetely not. None of these supplements have any antipsychotic properties. If you try to replace your antipsychotic with these then pretty soon you’ll think you can fly and jump off a building.
From another thread…
lorcaserin treatment could counteract the metabolic effects of olanzapine. Co-treating with lorcaserin prevented weight gain and significantly improved the metabolic profile of mice treated with olanzapine
Lorcaserin is associated with certain types of infections. If it were that easy, more people would be on it when I think it’s probably very rarely used. Tread carefully when learning about your health on the internet is what I’ve learned the hard way.
Day 1 and Day 2 - 100mg of L-Theanine twice a day with 7.5mg of Olanzapine once a day.
Result - Feeling of dread, state of confusion but reduced voices in the head. Cannot separate reality and illusion.
Anxiety, Confusion and moderate delusions.
Day 3 -
Morning - 200mg of L-Theanine with 7.5mg of Olanzapine
Result - Still anxiety and confusion after 30 mins.
It worked. It worked.
Anxiety is under control - the feeling of dread is gone.
Takes an hour to an 1.5 hours for the effects. And 200mg of theanine twice a day seems to work.
From another blog…
It is not entirely clear why relapsing happens, but for most people it is related to stress. Stress can present in many forms. Some research and surveys of people with the illness suggest the following to stay healthy (avoid relapses):
Take medications as prescribed
Avoid travel
Staying healthy (exercise, sleep, eating healthy foods, etc)
Maintaining supportive family relationships
Maintaining social connections- having friends
Not living alone- roommates or having pets
Having interests- hobbies, etc.
Avoiding drugs or alcohol
Avoiding isolation
Avoiding crowdsAnother external cause cited is copper-toxicity…
Get heavy metals lab test results for your food, water, supplements or hair.
Dr. Lawrence Wilson published the following tips for reducing excess copper and suggests safely combining multiple methods at once:
Reduce exposure to sources of copper – Avoid or decrease exposure to IUDs, public swimming pools and high-copper foods such as avocado, nuts, seeds, wheat, shellfish and soy.
Diet is critical – Consume a combination of cooked vegetables, organic animal protein (if possible) and whole grains, and avoid stimulants such as sugar, caffeine and food additives.
Lifestyle modification – Reduce stress factors by making changes in work, relationship and spiritual arenas.
Choose nutritional supplements to support adrenal gland function and balance copper – According to Wilson, a hair mineral analysis and consultation with a physician or homeopath will provide answers as to which supplements will work for each individual.
Detoxification procedures – According to Wilson, detox methods like coffee enemas and infrared lamps can be beneficial, but cleansing diets, foot baths and clays are less effective and cause interference.
Day 3 evening - 2x Cod Liver Oil 300mg, 2x L-theanine 100mg, 1x pill B-complex+Vit C+Zinc, 1x 7.5mg Olanzapine
Improved Cognition, some conversation. Still confusion. Still a bit anxious. No voices, no delusions.
I think you’re mistaken here with regard to Olanzapine - there is one study that showed no added positive effect of sarcosine with clozapine, but there is no study that shows sarcosine is not helpful with Olanzapine.
If you read the study you just referred to - you can see that they had an issue with the venlafaxine and lowered it and then the patient was fine and doing well again (better than before the sarcosine) with both sarcosine and olanzapine.
Here is what it says:
“We diagnosed drug-induced hypomania and recommended decreasing the daily dose of venlafaxine to 37.5 mg per day, which resulted in normalization of mood and activity in about 1 week. After this change, activity and mood remained stable and better than before adding sarcosine, and subsequent depressive symptoms were not noted.”