Karuna Therapeutics at Goldman Sachs 41st Annual Global Healthcare Conference

We are an innovative clinical-stage biopharmaceutical company primarily focused on developing novel therapies to address disabling neuropsychiatric conditions characterized by significant unmet medical need.

Our pipeline is built on the broad therapeutic potential of our lead product candidate, KarXT, an oral modulator of muscarinic receptors that are located both in the central nervous system, or CNS, and various peripheral tissues. KarXT is our proprietary product candidate that combines xanomeline, a novel muscarinic agonist, with trospium, an approved muscarinic antagonist, to preferentially stimulate muscarinic receptors in the CNS.

2 Likes

The video discussion is very encouraging in terms of efficacy, effect size, and side effects.

1 Like

Side effects: they reported mild, with no severe adverse effects and no one dropped out due to side effects.

They also reported that side effects decreased over the study, that is people experienced a side effect but it didn’t last.

1 Like

Sounds good. No dopamine receptor binding = no negative symptoms. That’s my hope anyway. Would love to see a similar podcast for SEP 363856.

1 Like