Good news cant cure …hahahahaha… sup exhile.?? Good morning …ur jog finished …!!!
Hi Niraj, the news article isn’t a cure but can predict those that may develop schizophrenia. Going to jog later this afternoon… just finished shoulders… how have you been?
Keep posting news @exhile !
News is very important!
Thank you.
@Erez_Shmerling I’ll try my best to post positive news about schizophrenia.
They should let these supercomputers/AI thingy figure out what is wrong with our brains. You just give them all the data: genes, hormone levels etc and they’ll have an answer in about 6 to 12 months.
Theonly thing that’s missing though is machines that can see what is happening in our brains and produce extra data to give to ai.
Because the problem is twofold 1. We don’t have a good enough picture and understanding of what is happening to our brains. 2. Even if we had all the info, humans are not smart enough to understand what is happening and develop a clear picture.
@GentleSoul IBM Watson is an A.I. computer that uses an MRI scan of a person’s brain to determine deficiencies in blood flow. This technology will assist in determining if a patient will develop schizophrenia or not.
Once the person is schizophrenic can the ai computer get a clear and global picture of the brain’s malfunctioning?
Did u know that Watson’s son is schizophrenic?
@GentleSoul Most likely the A.I. computer will acquire the data about the patient’s brain and the regions where blood flow is lacking.
Thomas Watson III or Thomas Watson Jr. both or either of which may have suffered from depression but that’s all I could find on the Internet. I don’t know if either were schizophrenic.
There is some effort to track response in drug trials based on genetic makeup and SNPs. One such company(Denovo) bought the rights to a failed drug candidate LY2140023 because it may be effective in a smaller subset of patients with a specific genetic makeup. So, if companies are willing to share (and trial participants too) there is actually a lot of data on the response for particular genes and the protiens they code for. This is all in the lab at this point though. Most of the modern trials now include brain scans as well.
@twinklestars Usually drug companies will patent a new drug and try to increase revenue from it. So, it’s not for the sake of someone’s health but for the company who developed the drug to survive.
But, frequently the drugs fail because they are tested in broad categories of patients. So if the drug fails, but like 5 people out of 80 got substantially better, there are some companies who will investigate why and then buy the rights to the drug, which the original company is no longer persuing. They might work out a sale or licensing agreement.
As far as I know, no drug approvals have yet come from this, but it is a step towards personalized medication.
@twinklestars Biotechnology is a tricky business since patient trials have to succeed in order for the drug to be approved. Many biotech companies have ceased operations because their drugs failed on patients.
I don’t think there is personalised medication but a variety of medication to reduce a common symptom. I’m not a pharmacologist or a doctor but this is what I know.
It certainly is a tricky business. Here is the article on Denovo’s acquisition of the failed drug.
And here’s what Denovo does:
https://www.denovobiopharma.com/index4.html
Some people have specific genetic makeup that either prevents them for metabolizing a drug, or they have a particular SNP that the drug may work particularly well for, and this is the sort of thing AI would be invaluable for.
Here is where he talks about his son, if I recall correctly.
@twinklestars There are many drug companies in this situation and it’s not just treatment for schizophrenia. Various types of cancers, multiple sclerosis, even antibiotics for the common cold & cough have to go through this vigorous testing.
Presently IBM’s A.I. computer is used for treating cancer patients by storing a huge knowledge base in its memory.
https://en.wikipedia.org/wiki/Watson_(computer)#Healthcare
Yes, many. Of course my interests are somewhat more limited.