Duloxetine (Cymbalta) as an add-on to risperidone seems to be a tolerable and efficacious treatment for primary negative symptoms of schizophrenia.
Full research paper is available for free on Sci-hub.cc
(You will need to enter a “captcha” from the page to get access. This is a good site - don’t be put off by the fact that its in russian language. The paper is in English)
I’ll talk about it with my pdoc. He once tried to prescribe me Cymbalta (duloxetine) but I refused. Now I might change my mind after reading this (even though I’m biased against Iranian researchers but that’s another story).
I have now been taking duloxetine for the past 7 weeks. Started with 30mg then went up to 60 mg/day. Sadly, nothing has changed as regards my negative symptoms.
How you know what is the difference between negative symptoms and depression and can you give more details how duloxetine help you what wonders do for depression ?