Cognitive functioning as a predictor of response to comprehensive cognitive remediation

firemonkey · April 2, 2019, 4:37pm

ncbi.nlm.nih.gov

Cognitive functioning as a predictor of response to comprehensive cognitive remediation.

NR DeTore, KT Mueser, JA Byrd and SR McGurk, Journal of psychiatric research, Mar 21 2019

Cognitive remediation is aimed at reducing cognitive impairments in severe mental illnesses such as schizophrenia, but little is known about whether severity of cognitive impairment predicts benefit from this intervention. To address this question, this study aggregated data from five randomized controlled trials (N = 300) of a standardized comprehensive, multimodal outpatient cognitive remediation program, the Thinking Skills for Work program, and evaluated whether baseline level of cognitive impairment differentially predicted improvement in cognitive functioning following cognitive remediation vs. usual services. Using standardized scores of neuropsychological functioning to designate "low average," "moderate," and "severe" levels of cognitive impairment, participants with greater cognitive impairment were found to benefit differentially more from cognitive remediation than usual services compared to less cognitively impaired participants. The findings were unaffected by statistically controlling for participant demographic and clinical characteristics. The findings suggest that individuals with the greatest cognitive impairment, for whom cognitive remediation was developed, are also most likely to benefit from this intervention.

twinklestars · April 2, 2019, 4:41pm

Just want to highlight that.

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Cognitive functioning as a predictor of response to comprehensive cognitive remediation

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