Clozapine shows a greater clinical improvement in schizoaffective and bi-polar than patients with schizophrenia



The findings of this study confirm the efficacy and safety of clozapine for treatment-resistant patients with a diagnosis of schizophrenia, schizoaffective disorder, or bipolar disorder with psychotic features. Patients with schizoaffective disorder and those with bipolar disorder show greater clinical improvement than those with schizophrenia. Patients with bipolar disorder have the shortest time to response and the highest psychosocial and occupational functioning levels. Patients with schizoaffective disorder have the lowest treatment discontinuation rate.


So if you have just schizophrenia it is less likely to work.


That’s what it looks like. What do you have @GrayBear?


Just your average run of the mill schizophrenia :sunglasses:


Also found this.

Manic symptomatology predicts a more favorable response than depression.


That’s really interesting, 48 months! Possibly this is something the family forum would like.