Breakthrough RNA editing techniques could change how genetic disease is studied and treated

https://gizmodo.com/breakthrough-technique-could-revolutionize-the-way-scie-1819820539?

“Where the REPAIR system could be a game-changer is in allowing scientists to alter disease-causing mutations without actually permanently changing a person’s genetic code. By correcting problematic mutations to the letters that encode RNA, scientists could potentially reverse mutations without causing permanent change to the genome, since RNA degrades naturally over time.”

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May you be blessed for eternity @twinklestars,
thank you for posting this.
I hope it leads to better practical treatments for schizophrenia.

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This is big, Feng Zhang has had a interest in schizophrenia for along time so I have been keeping an eye out on what he’s been up too, Looks like hes been hard at work and REPAIR might be one of the miracles needed to cure us. :slight_smile:

@far_cry0 this might be what you where waiting for from the broad.

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It is big. It’s an exciting time to be alive.

And yes, it’s far from the clinic, but CRISPR cas9 was first used for genome editing in 2013 by this same person, Feng Zhang and others in his research group. And look how fast cas 9 has advanced research in just a handful of years.

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@far_cry0 RNA editing is a solution to those ethical issues presented by CRISPR, I was telling u about. If Zang doesn’t get a Nobel price, …

“More interesting, perhaps, is the way in which RNA editing could reframe the ethical debate around gene editing. Many concerns stem from the fact that altering someone’s genome is permanent; an edit that comes with unintended consequences could last forever, and even be passed down through generations. For some diseases, though, editing RNA could offer a workaround.”

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You’re not wrong, but if we can edit the genome, gene editing isn’t “permanent” you could potentially change it back. But yeah, it should help alleviate some concern.

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Hi my man opus …!!! Now i am intrested towards finding the real causes of schizophrenia genetic causes…after that they will devise effective pills to manage sz…then i will be happy…

Do u belive in what i say…!!!