Brain changes in puberty in people with 22q11.2 deletion may explain their increased risk of schizophrenia and autism:
# Puberty triggers brain rewiring in genetic condition tied to autism, mouse study suggests - Medical Xpress
Changes in brain connectivity before and after puberty may explain why some children with a rare genetic disorder have a higher risk of developing autism or schizophrenia, according to a UCLA Health study.
Developmental psychiatric disorders like autism and schizophrenia are associated with changes in brain functional connectivity. However, the complexity of these conditions make it difficult to understand the underlying biological causes. By studying genetically defined brain disorders, researchers at UCLA Health and collaborators have shed light on possible mechanisms.