A potential new approach for the treatment of schizophrenia

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Found this while searching for some good news on sz. Tired of seeing only negative articles.

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I hope you’re right and that there is no permanent negative and cognitive symptoms.

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Any mGlur1 agonists? I will google that.

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Idk much about mGlur receptors but I read they’re involved in brain development. I hope its not too late to fix it.

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I read “new approach” and immediately wondered…

Are they sneaking up on it from behind now?

I haven’t tried that. Could work.

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Related article:
https://www.cell.com/cell-reports/fulltext/S2211-1247(21)01427-3?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS2211124721014273%3Fshowall%3Dtrue

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Study; “These findings support the use of group I mGluR antagonists as a potential therapy that extends to autism models involving exacerbated mRNA translation initiation.”

Excessive mGluR1 & mGluR5 are linked to ASD. This new mGluR based treatment for SCZ therefore might have unattended long term side effects. Who knows . . .

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I read about how the mglur5 receptor being enhanced indirectly affects the nmdar receptor. I think similar to how sarcosine would affect it.

https://www.jbc.org/article/S0021-9258(20)84497-4/fulltext

There’s a racetam nootropic called fasoracetam that is a mglur non selective agonist. It’s an unregulated supplement so it would be tough to know if it was quality.

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If you just read the conclusions it can tell you about how sarcosine affects these receptors

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