A new generation computerised metacognitive cognitive remediation programme for schizophrenia (CIRCuiTS): a randomised controlled trial

anon79999497 · September 5, 2017, 12:41pm

ncbi.nlm.nih.gov

A new generation computerised metacognitive cognitive remediation programme for schizophrenia (CIRCuiTS): a randomised controlled trial.

C Reeder, V Huddy, M Cella, R Taylor, K Greenwood, S Landau and T Wykes, Psychological medicine, Sep 2017 04

Cognitive remediation (CR) is a psychological therapy, which improves cognitive and social functioning in people with schizophrenia. It is now being implemented within routine clinical services and mechanisms of change are being explored. We designed a new generation computerised CR programme, CIRCuiTS (Computerised Interactive Remediation of Cognition - a Training for Schizophrenia), to enhance strategic and metacognitive processing, with an integrated focus on the transfer of cognitive skills to daily living. This large trial tested its feasibility to be delivered in therapist-led and independent sessions, and its efficacy for improved cognitive and social functioning.A two arm single blind randomised superiority trial comparing CIRCuiTS plus treatment-as-usual (TAU) with TAU alone in 93 people with a diagnosis of schizophrenia. Cognitive, social functioning and symptom outcomes were assessed at pre- and post-therapy and 3 months later.85% adhered to CIRCuiTS, completing a median of 28 sessions. There were significant improvements in visual memory at post-treatment (p = 0.009) and follow-up (p = 0.001), and a trend for improvements in executive function at post-treatment (p = 0.056) in favour of the CIRCuiTS group. Community function was also differentially and significantly improved in the CIRCuiTS group at post-treatment (p = 0.003) but not follow-up, and was specifically predicted by improved executive functions.CIRCuiTS was beneficial for improving memory and social functioning. Improved executive functioning emerges as a consistent predictor of functional gains and should be considered an important CR target to achieve functional change. A larger-scale effectiveness trial of CIRCuiTS is now indicated.

far_cry0 · September 5, 2017, 2:07pm

We our country doesnt have such type of facilities in our country…

Topic		Replies	Views
A feasibility study of a new computerised cognitive remediation for young adults with schizophrenia News	2	606	March 11, 2015
Trial implementation of CIRCuiTS cognitive remediation therapy for people with schizophrenia News	3	341	November 1, 2019
A Multisite, Randomized Controlled Clinical Trial of Computerized Cognitive Remediation Therapy for Schizophrenia News	0	440	October 13, 2015
Combining social cognitive treatment, cognitive remediation, and functional skills training in schizophrenia: a randomized controlled trial News	1	781	November 11, 2016
Cognitive Remediation Can Boost Employment Rates for Schizophrenia Patients News	0	594	January 7, 2014

A new generation computerised metacognitive cognitive remediation programme for schizophrenia (CIRCuiTS): a randomised controlled trial

Related topics