but brain according to some people
very complicated most complicated
we need bypass digestive system and medication go to blood
by pass liver this called first pass effect and go to brain
bypass blood brain barrier around brain
target specific areas in brain
know the right place in brain and the right receptor we need to target
and we need this knowldge to be right
we also need to guarantee this drug reach its place not another place which cause side effects coz human body is also very complicated
avoid side effects as much as possible in short term and long term
sorry for your suffer and my suffer 
