Sometimes 600 mg seroquel does not work

It is quite a heavy dose I take plus other meds each evening, as I did not get any sleep tonight it does not work always.i have been taking these doses since 2011, 13 years.It should help me to sleep.

100mg put me out, even 50mg is putting me out now. I think over time we develop tolerance to these medications and they don’t work as well as they used to.

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