Some schizophrenia treatment are being delayed

Probably due to covid, ulotaront is planning to launch in 2024 instead of 2023

https://www.google.com/url?sa=t&source=web&rct=j&url=https://www.ds-pharma.com/ir/news/pdf/ebr20220131.2.pdf&ved=2ahUKEwjC4oii9OD1AhWvTmwGHSG4BfsQFnoECBgQAQ&usg=AOvVaw0sXDcIB31G7EqXxGOtVJ6f

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Does the Positive and Negative symptoms scale include cognitive symptoms?

No but it’s tested to treat cognitive symptoms as well since they gave the patient’s a cognitive test and they performed better on the medicine

The negative symptoms scale is self reported with a survey

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Taar1 agonists are known to improve cognition in rats and human

I see. This is good news. It is a pity that the release is being delayed.

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With covid, everything that can’t be done online are being delayed…sadly

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Yes, the covid story never ends, with new variants emerging almost everyday now.

I think this way it will remain with us for the next 50 years or until a substantial portion of the population develops immunity.

Is this medication being tried for Bipolar?

I have schizoaffective, so I was wondering if it may control the Bipolar aspect of the illness as well.

I see no bipolar trials, only schizophrenia, 1 Parkinsons psychosis and 1 schizotype Phase 1 trial from years ago.
bipolar search

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Tpo bad its getting released in 2024. That means it could be more then 2 years until its released in the usa. I was hoping to get put on it. I got a long wait though i need to wait for it to get approved in canada.

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Is the effect on cognition significant?

cognition study
This article says small cognition improvement during trial.

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Well this delay sucks.

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Did it pass all clinical trials? So it will be approved by the FDA for sure?

Probably not yet that’s why it’s delayed.

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3 trials still recruiting, 1 trial estimated to run till November at the earliest.Phase 3 trials

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I’m sorry, but I can’t see where did you see that information that it will not be launched in 2023… There is a document from December 2021 that it will be launched in 2023: https://www.ds-pharma.com/ir/news/pdf/eir20211208.pdf

There are 3 USA trials still recruiting with estimated completion date late 2022 at the earliest. After trials, it takes quite a few months to analyze data and publish results. It takes months to prepare New Drug Application. The FDA review and decision to deny or approve will take 6-9 months.

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