Schizophrenia.com

Scientists find gene fault that Increases schizophrenia risk 35-Times Higher

Scientists say they have conclusive evidence that changes to a gene called SETD1A can dramatically raise the risk of developing schizophrenia - a finding that should help the search for new treatments.

The team, led by researchers at Britain’s Wellcome Trust Sanger Institute, said damaging changes to the gene happen very rarely but can increase the risk of schizophrenia 35-fold.

Changes in SETD1A also raise the risk of a range of neurodevelopmental disorders, the researchers said.

In a study published in the journal Nature Neuroscience, the team found that mutations that remove the function of SETD1A are almost never found in the general population, but affect 1 in 1,000 people with schizophrenia.

Read the full story here:

http://neurosciencenews.com/genetics-schizophrenia-setd1a-1054/

and

http://news.yahoo.com/scientists-gene-fault-raises-schizophrenia-risk-35-fold-160139453--finance.html

Free access to the full research paper is here:

http://sci-hub.io/http://www.ncbi.nlm.nih.gov/pubmed/26974950

A summary is here:

http://sci-hub.io/http://linkinghub.elsevier.com/retrieve/pii/S0896-6273(16)00141-0

5 Likes

I wish everybody would just stop blaming Gene for a rise in schizophrenia. It really isn’t his fault at all. This bullying has got to stop!!

3 Likes

Gene shaming is all it is!! Gene is just expressing himself!

2 Likes

You guys make me laugh!

3 Likes

Ome. Gene, Ome. Genome.

2 Likes

This reminds me of Gene Rayburn. He was the host of Match Game in the 1970’s.

Here’s a funny Freudian slip of his from that era…