Schizophrenia Study Suggests Advanced Genetic Scorecard Cannot Predict a Patient’s Fate

https://www.newswise.com/articles/schizophrenia-study-suggests-advanced-genetic-scorecard-cannot-predict-a-patient-s-fate

With the help of cutting-edge computer programs, researchers at the Icahn School of Medicine at Mount Sinai went through the genetic and medical records of more than 8,000 schizophrenia patients. They found that a tool commonly used in research for evaluating a person’s genetic risk for a disease, called a polygenic risk score, was no better at predicting the outcome of a patient’s disease over time than written reports. The results raise important questions about the use of polygenic risk scores in real-world, clinical situations, and also suggest that a doctor’s written report may be an untapped source of predictive information.

3 Likes